POTS – Postural Orthostatic Tachycardia Syndrome, Myocarditis & COVID Shots
Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-Cov-2 Infection Alan C. Kwan 1 , Joseph E. Ebinger 1, Janet Wei1, Catherine N. Le2, Jillian R. Oft2, Rachel Zabner2, Debbie Teodorescu1, Patrick G. Botting1, Jesse Navarrette1, David Ouyang 1, Matthew Driver1, Brian Claggett3, Brittany N. Weber3, Peng-Sheng Chen1 & Susan Cheng 1
This study was done in Los Angeles and Boston in 2022 and involved 284,592 vaccinated patients. Patients received Pfizer (62%), Moderna (31%), or Johnson & Johnson (6.9%) [less than 0.1% received another product such has AstraZeneca or Novavax]. They compared medical diagnoses that occurred within 90 days after vaccination compared to the 90 days before vaccination. The three diagnoses that had the highest post-vaccination odds were myocarditis, dysautonomia, and POTS.
Myocarditis risk increased by 157% [OR 2.57 (95% CI: 1.02-6.77, p = 0.046)].
Dysautonomia risk increased by 124% [OR 2.24 (95% CI: 1.30-3.87, p = 0.002)].
POTS risk increased by 52% [OR 1.52 (95% CI: 1.36-1.71, p < 0.001)].
Note the gender differences. Myocarditis was more common in males. POTS was more common in females.