COVID-19 Vaccination and Cardiovascular Events: A Systematic Review and Bayesian Multivariate Meta-Analysis of Preventive Benefits and Risks Karimi, Raheleh1,2; Norozirad, Mina3; Esmaeili, Foad4; Mansourian, Marjan2,5; Marateb, Hamid R.6,7,8 International Journal of Preventive Medicine 16():14, March 2025. | DOI: 10.4103/ijpvm.ijpvm_260_24
This was a large meta-analysis reviewing 15 studies involving about 85 million people (45 million vaccinated, 40 million unvaccinated) from multiple countries across Asia, Europe, and North America. It was published in March 2025. Few controlled Moderna studies were available, so this study focused on the Pfizer (BNT162b2) and Astra Zeneca (ChAdOx1) shots.
Figure 4: Subgroup analysis for arrhythmia, MI, CVD, and Stroke events following COVID-19 vaccination
Karimi, Raheleh1,2; Norozirad, Mina3; Esmaeili, Foad4; Mansourian, Marjan2,5; Marateb, Hamid R.6,7,8
COVID shots increased the risk of the following events/diseases:
Coronary Artery Disease (CAD)
Overall: 70% increased risk [OR 1.70 (95% CrI: 1.11-2.57)]
Pfizer: 64% increased risk [OR 1.64 (95% CrI: 1.06-2.55)]
2nd dose all vaccines: 244% increased risk [OR 3.44 (95% CrI: 1.99-5.98)]
Myocardial Infarction (MI)
2nd dose all vaccines: 286% increased risk [OR 3.86 (95% CrI: 2.28-6.60)]
Pfizer: 87% increased risk [OR 1.87 (95% CrI: 1.22-2.89)]
Pfizer 2nd dose: 284% increased risk [OR 3.84 (95% CrI: 2.21-6.66)]
Stroke
Pfizer: 109% increased risk [OR 2.09 (95% CrI: 1.36-3.21)]
Pfizer 1st dose: 269% increased risk [OR 3.69 (95% CRI: 2.13-6.37)]
All vaccines 1st dose: 240% increased risk [OR 3.40 (95% CrI: 1.98-5.86)}
Arrhythmia
All vaccines 1st dose: 199% increased risk {OR 2.99 (95% CrI: 1.20-7.44)]
AZ: 711% increased risk [OR 8.11 (95% CrI: 3.67-17.99)]
AZ 1st dose: 389% increased risk [OR 4.89 (95% CRI: 1.21-19.38)]
How can anyone look at this data and say the COVID shots are safe? They are not safe. They are dangerous and they are deadly…